Mental healthdisorders like depression may requireantidepressantsto treat. The signs and symptoms of anaphylaxis include dizziness or fainting, skin flushing and itchiness, difficulty breathing, rapid heart rate, low blood pressure and sudden anxiety. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. As with most drugs, some people can have an allergic reaction after taking Injectafer. The drug helps increase your hemoglobin level back to a value thats within the normal range. HRT, like other medications, does have some side effects and these are thought to be quite common. (A generic drug is an exact copy of the active drug in a brand-name medication.) If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. People in the study received treatment with either Injectafer or Venofer. However, many people have no side effects or only have minor side effects. generalized weakness. Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. However, side effects at the 150 mg dose may indicate that you might not . The use of Injectafer and Feraheme in treating IDA in these adults has been directly compared in a clinical study. Its not known if Injectafer is safe to take during pregnancy. Tell your doctor if you are taking iron supplements or other iron-based oral medications. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. Dr. Colby is alsothe Founder of Sequencing.com and the authorofOutsmart Your Genes. Learn more about these, as well as the symptoms, diagnosis, and treatments. Together, you and your doctor can develop a treatment plan thats best for you. This information is not specific medical advice and does not replace information you receive from the healthcare provider. But for other people, their anemia may come back after Injectafer treatment. The oral form of the drug, called sucroferric oxyhydroxide and used . The following information is provided for clinicians and other healthcare professionals. It can be given as a slow injection over 2 to 5 minutes or as an infusion. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. Details. To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. Check with your pharmacist. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Vomiting. You may also need to monitor your blood pressure at home. Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. Talk to your pharmacist for more details. All of the people took iron by mouth for 2 weeks. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Tell your caregivers right away if you have: problems with your dialysis vein access point; high blood pressure - severe headache, blurred vision, pounding in your neck or ears; low blood pressure - a light-headed feeling, like you might pass out; or. Before taking Injectafer, talk with your doctor about your health history. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre taking Injectafer. In the first group, some people continued taking iron by mouth, while other people took Injectafer. weakness. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. Venofer Side Effects. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. Talk with the doctor. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. If you have questions about using Injectafer in a child, talk with your doctor. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. With slow IV injection, the drug is given as a single, slow injection into your vein. For more information and to find out if youre eligible for support, call 877-4-IV-IRON (877-448-4766) or visit the program website. Some drugs may have another patient information leaflet. Do not flush down a toilet or pour down a drain unless you are told to do so. Your doctor will do laboratory tests to monitor your response. Venofer is for use in adults and children at least 2 years old. For example: Say you weigh 105 pounds (about 48 kilograms). Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. Taking a larger dose of LSD can extend the duration of the trip, but generally, the main effects of LSD don't tend to last any longer than 12 hours. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. Most people do not know how long theirside effectswill last until they go through them. For instance, someone with lowblood pressuremay receive a medication to prevent migraines that lowersblood pressure, this may causeseriousside effects. And this can affect how well those parts of your body are able to work. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Venofer only for the indication prescribed. It is very important that your doctor check you closely while you are receiving this medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. Together, you and your doctor can discuss the benefits and risks of treatment options for anemia. The researchers looked to see how well each drug worked to increase peoples hemoglobin level. With IDA, you have low hemoglobin levels. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. Tell your doctor if you are pregnant or plan to become pregnant. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. You are encouraged to report side effects to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. However, consuming large amounts of alcohol can actually cause anemia in some people. Theseside effectsmay last as long as they are undercancer treatment. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. Potential injection site discoloration has happened. Theyll do this by checking certain blood tests. A healthcare provider will give you this injection. Be ready to tell or show what was taken, how much, and when it happened. Back pain. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. Your doctor will go over your Precautions. People with IDA have low blood levels of hemoglobin. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. One study of just under 5000 HRT users found that 43% were affected. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. Injectafer contains the active drug ferric carboxymaltose. xmq92\Kz!yIP}2~(?c/JUCK2~o_N=>K$o/_7'Z+nRkKM^y{u|ZFh$v}]O~vfo=.GowGFodVj-[-~x]Kg~9H'%h={OX/#S|Mc~|]_2nv`wwotn/+$G[{hGrP}sbZG-RGf#l~~l|Qnccml_iPy]G\17c,yPF[28z&I'+B(?rrvi,G?}/;'?;pm>?.i42ONmk~ai_u0z9o_? Consult the product instructions and your pharmacist for storage details. Or your doctor may recommend that you change your eating habits to include more iron in your diet. Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. Patients with celiac disease (gluten intolerance). A variety of tests can diagnose iron deficiency anemia. Before using iron sucrose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. But keep in mind that in this study, delayed allergic reaction only occurred in one person. pain or burning at the injection site. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Injectafer contains the active drug ferric carboxymaltose. And theyll recommend how soon after starting the drug you need to have this level checked. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. This hormone is made by your kidneys. Do not start, stop, or change the dose of any drug without checking with your doctor. Iron sucrose can also be mixed in a. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. This medication is given by injection into a vein as directed by your doctor. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). (A class of medications describes a group of drugs that work in the same way.). I'm contemplating getting infusions again but I've always been a bit worried that they could cause issues in the long run. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. Keep all drugs in a safe place. If you have questions about using Injectafer for anemia during pregnancy, talk with your doctor. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Their medical staff can help you set up another time to receive your Injectafer dose. Infusions should be administered over at least 15 minutes. signs of inflammation in the lining of your stomach --pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. However, diarrhea it isnt very common in people using Injectafer. Low iron saturation, or iron deficiency, has various possible causes. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. These symptoms can include: While youre taking Injectafer, your doctor will monitor your phosphorus levels if youre at risk for hypophosphatemia. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. 2023 Medicine.com All rights reserved. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). Symptoms include shock, dangerously low blood pressure, loss of consciousness, and/or collapse. Its not known whether its safe to breastfeed while youre taking Injectafer. fluid retention, especially in your arms, legs, or feet, people who took Feraheme had their hemoglobin level increase, on average, by 1.38 grams per deciliter (g/dL), people who took ferric carboxymaltose had their hemoglobin level increase, on average, by 1.63 g/dL, having strange cravings to eat items that arent food, such as ice, people who took Injectafer had their hemoglobin level increase, on average, by 1.6 grams per deciliter (g/dL), people who kept taking iron by mouth had their hemoglobin level increase, on average, by 0.8 g/dL, people who took Injectafer had their hemoglobin level increase, on average, by 2.9 g/dL, people who took the other intravenous iron product had their hemoglobin level increase, on average, by 2.2 g/dL, people who took Injectafer had their hemoglobin level increase by an average of 1.1 g/dL, people who took Venofer had their hemoglobin level increase by an average of 0.9 g/dL, cannot tolerate or have shown a poor response to oral iron, or, have been diagnosed with chronic kidney disease (CKD) that is non-dialysis dependent. Change in taste. I got Venofer twice in the last few years and now my iron deficiency is worse than ever, first time my hemoglobin is down to 11,2. Effectiveness of Injectafer compared with iron thats taken by mouth. Its not known how often people taking a treatment other than Injectafer had diarrhea. If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. There are currently no generic forms of either drug. Fortunately, knowing how longside effectslast can help those suffering know what to donext. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. treatment schedule in further detail. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. Note: The Food and Drug Administration (FDA) tracks side effects of drugs they have approved. upper respiratory infection. Then the study was split into the following two groups, which are discussed below. Hes an expert in genetic testing, genetic analysis, andprecision medicine. <> Injectafer isnt known to interact with any other medications, herbs, supplements, or foods. Side effectsare uncomfortable reactions to medications or drugs. Follow all instructions closely. However, since peoples bodies react so differently to drugs, they often have to change their stance on certain drugs. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. This website is intended for use by US healthcare professionals only. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Learn more about the types of tests and treatment. Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. Should I avoid certain foods while taking Venofer Vial? Theseside effectscan range from being mild tosevere. Injectafer is available only as a brand-name medication. Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. Undergoingcancer treatmentwithradiation therapyorchemotherapy drugsmay result inhair loss, which can be devastating to somepeople. signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. Injectafer is a brand-name prescription drug. To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. 5 0 obj Your healthcare provider will watch you closely for 30 minutes after each dose. This may be helped by giving the medication more slowly or at a lower dose. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. They can recommend appropriate treatment options. In this study, researchers compared Feraheme treatment with that of ferric carboxymaltose (the active drug in Injectafer). Some products that may interact with this drug include: vitamin products, other iron-containing products. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. So we cant say for sure whether the drug is safe to use while youre pregnant. Canada residents can call a provincial poison control center. And this person had gotten their first dose of the drug without having an allergic reaction. I had my first infusion of 1gm 10 days ago. (For more information on Venofer, see the Injectafer vs. Venofer section above). Iron-refractory iron deficiency anemia (IRIDA) is a genetic form of anemia. With this condition, you also have a low hemoglobin level. People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each.
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